The Relationship of Chronic Pulmonary Diseases and Asthma With Blood Groups in Hospitalized Patients

Introduction: Considering the high prevalence of respiratory diseases, it is important to identify factors affecting them, especially the role of genetics and blood antigens. By identifying people with a high risk of developing asthma and chronic pulmonary diseases, it is possible to take diagnostic measures and perform proper screening to observe the improvement of patients’ quality of life and the increase of proper screening. Therefore, the aim of this study was to determine the relationship between blood group types and the occurrence of chronic pulmonary diseases. Methods: The present retrospective study was conducted on patients with asthma and chronic obstructive pulmonary disease (COPD) in 2018. Overall, 30 patients with asthma, 70 patients with COPD, and 100 patients in the control group were evaluated in this study. Finally, the obtained data were entered into SPSS version 22 software and subjected to statistical analysis with t-test, Chi-square, and Fisher’s exact tests. Results: The results of the present study revealed that the most frequent blood types in asthma, COPD patients, and the control group were A (38.09%), B (40.42%), and O (41.66%), respectively, which were statistically significant (P=0.003). Blood group A had a significant relationship with the gender of asthmatic patients, and blood groups A and B had a meaningful relationship with positive family history in asthmatic patients. Conclusion: In this study, a significant relationship was observed between blood group A and asthma, as well as blood group B and COPD, compared to the control group.