Author/Authors :
Mahmoodnia ، Leila Department of Internal Medicine - School of Medicine, Hajar Hospital - Shahrekord University of Medical Sciences , Forouzandeh Shahrakei ، Zahra Deputy of Research and Technology - Shahrekord University of Medical Sciences , Hojatyar ، Sanaz Student Research Committee - Shahrekord University of Medical Sciences , Setorki ، Mahbubeh Department of Biology - Islamic Azad University, Izeh Branch
Abstract :
Introduction: Diabetes mellitus remains one of the most prevalent metabolic diseases and a major health concern, despite the availability of a variety of synthetic drugs for its treatment. The multiple consequences of this disease, combined with the potential side effects of chemical treatments, led to the study of other therapies, such as the use of medicinal plants renowned for a variety of active components. Given the historic usage of medicinal plants for diabetes treatment, the aim of this study was to investigate the impact of lavender (Lavandula officinalis) hydroalcoholic extract on specific blood and urine biochemical factors in diabetic patients. Material Methods: In this double-blinding clinical trial, a total of 72 diabetes patients were divided into two groups: a control group that received a placebo and a treatment group that received the lavender hydroalcoholic extract. Capsules containing the lavender extract were formulated to be administered. The placebo capsules were given to the control group, while the lavender extract capsules were given to the treatment group twice a day, once in the morning and once at night, for two months. All patients underwent blood biochemical testing and urine analysis at the beginning and end of the trial. The data collected were analyzed using the SPSS 18 software. Results: Compared to the placebo group, the mean HDL-C increased and the average levels of FBS, LDL-C, VLDL-C, TG, Chol, AST, and ALT became significantly lower (P 0.05) in the patients who received capsules containing lavender extract. Likewise, the urine protein and sugar levels in the patients who received the lavender extract group were significantly lower (P 0.05) compared to the control group. Yet, the average changes in BMI did not differ significantly between the groups receiving lavender extract and the placebo (P 0.05). Conclusion: The lavender plant with different phenolic and flavonoids compounds could reduce blood sugar and also improve lipid profile in people with diabetes.
