Correlating Serum Adropin Levels with Blood Coagulation Indices across Physical Activity Levels in Young Adults

Introduction: Evidence suggests a link between serum adropin levels and coagulation factors, with physical activity boosting adropin circulation. This study investigates the correlation between adropin and blood coagulation factors in young adults at varying activity levels. Material Methods: Fifty healthy young adults were divided into active and inactive groups using the Baecke questionnaire. Blood samples assessed adropin and coagulation factors. Statistical tests included Mann-Whitney and independent t-tests for comparison, with Spearman’s correlation coefficient determining strength. Results: Active participants exhibited significantly lower fibrinogen (p 0.05) and higher adropin levels (p 0.05) compared to inactive peers. Physical activity correlated negatively (r=-0.27, p=0.05) with fibrinogen but not with adropin and other coagulation factors. Conclusion:  Elevated physical activity levels correlate with heightened serum adropin and reduced serum fibrinogen. Moreover, serum fibrinogen, a critical coagulation factor influencing blood clot formation, appears particularly sensitive to the effects of physical activity.