Title of article
Synthesis, Spectral and Biological Studies of DHA Schiff Bases
Author/Authors
BhagwatraoBiradar ، Shubham Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur , Narte ، Dnyaneshwar Vithal Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur , Kale ، Rushikesh Pradip Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur , Momin ، KalimoddinInayatsab Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur , Sudewad ، Maroti Sayabu Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur , Tayade ، Kundan Chandramani Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur , Palke ، Dhananjay Gangadhar Department of Chemistry - Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur
From page
41
To page
47
Abstract
A new series of Schiff bases derived from DHA (Dehydroacetic acid) and aromatic primary amines were synthesized and characterized by elemental and spectral (Electronic, IR and 1HNMR) analysis. The signals of 1HNMR spectrum and characteristic peaks in IR spectra are used for the molecular structure elucidation of synthesized Schiff bases. The antimicrobial activities of synthesized compounds have been screened in vitro against Escherichia coli, Staphylococcus aureus, Bacillus subtilis bacterial species, Candida albicans and Aspergillus niger fungal organism and found to exhibit strong antifungal activity than antibacterial activity. Among the studied DHA Schiff base of 2-amino-4,6-dimethylpyrimidine depicted discerning antifungal and antibacterial activities.
Keywords
Dehydroacetic acid , Schiff bases , Spectral and Biological study
Journal title
Journal of Applied Organometallic Chemistry
Journal title
Journal of Applied Organometallic Chemistry
Record number
2772093
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