Title of article :
Novel applications of alginate, cellulose, and collagen biopolymers in antimicrobial formulations and tissue engineering: A concise review
Author/Authors :
Bahari Golamkaboudi ، Ali Organ Procurement and Transplantation Multi-Disciplinary Center, Razi Hospital, School of Medicine - Guilan University of Medical Sciences , Babaeian Roshani ، Kosar Department of Medicine - Guilan University of Medical Sciences , Taheri ، Zahra Department of Biology - Islamic Azad University, Tehran Science and Research Branch
Abstract :
The objective of tissue engineering is the application of biomaterials in three-dimensional (3D) scaffolds to improve whole organs or damaged tissues. Natural polymers as unique biomaterials on the micro- and nanoscale have shown promising applications in tissue engineering, infected wound healing, and antibiotic delivery. Among these biopolymers, alginate, cellulose, and collagen have obtained significant attention in bone regeneration, cartilage repair, tissue healing, microbial-infected wound healing, and 3D scaffolds for cell therapy in different micro- and nanoformulations involving hydrogels, sponges, microspheres, microcapsules, foams, nanofibers, polymeric nanoparticles. Furthermore, immunogenicity and microbial infections present a potential health risk during tissue engineering and tissue implant. This concise review provides recent progress and clinical limitations of the applications of alginate, cellulose, and collagen in tissue engineering and antimicrobial micro- and nanoformulations.
Keywords :
Bone regeneration , Cartilage repair , Hydrogels , Sponges , Microcapsules , Polymeric nanoparticles , Nanofibers
