Author/Authors :
Fatahi ، Majid Student Research Committee - Lorestan University of Medical Sciences , Khanizadeh ، Sayyad Department of Virology - School of Medicine - Lorestan University of Medical Sciences , Safarzadeh ، Ali Department of Biology - University of Padova , Alamdary ، Ashkan Department of Biology - Islamic Azad University, Science and Research Branch , Razavi Nikoo ، Hadi Department of Microbiology - Infectious Disease Research Center, Faculty of Medicine - Golestan University of Medical Sciences , Mohammadi ، Rasool Department of Biostatistics and Epidemiology - School of Public Health and Nutrition - Lorestan University of Medical Sciences , Ghalandarian ، Annahita Student Research Committee - Lorestan University of Medical Sciences , Ajorloo ، Mehdi Blood Transfusion Research Center - High Institute for Research and Education in Transfusion Medicine
Abstract :
Background and Aim: The novel coronavirus 2019 can lead to a vast range of respiratory complications, from mild to severe, driving to acute respiratory distress syndrome (ARDS). Common symptoms of COVID-19 include fever, fatigue, and dry cough, which can lead to complications, such as gastrointestinal disorders, and liver, cardiac, and renal dysfunctions. Alteration in the hematological markers is one of the COVID-19 diseases evaluated by our study. Materials and Methods: In this study, hematological markers, including the levels of ESR, BS, Hb, HCT, MCV, MCH, MCHC, platelet, WBC, RBC, neutrophil, and lymphocyte, have been assessed and compared in both case and control groups. Furthermore, we assessed the associations between hematological parameters, clinical manifestations, and underlying medical conditions. Results: Our data showed that RBC, HCT, and ESR were significantly associated with the novel coronavirus 2019 infection according to the disease progression. ESR (P= 0.022), Hb (P= 0.032), and BS (P= 0.01) levels in male people infected by SARS-CoV-2 proved to have a significant relationship with the control group. Moreover, BS, Hb, HCT, ESR, and neutrophil showed significant variations in diabetic individuals suffering from SARS-CoV-2 infection. Conclusion: The dropping of the hematological markers in COVID-19 is linked with a noticeably increased mortality rate, while high neutrophil and BS levels are related to aggravation of the disease. Monitoring the hematological markers can contribute significantly to selecting the proper treatment and hamper of disease worsening.
Keywords :
COVID , 19 , SARS , CoV , 2 , Hematological , Marker ,
