Title of article :
Cytotoxic study of green synthesized pure and Ag-doped α-Fe2O3 nanoparticles on breast cancer (MCF-7) cell line
Author/Authors :
Esmaeilzadeh ، Amir Abbas Salamat yar behesht dayan - Dayan biotech company , Rasoolzadegan ، Soheil Department of Neurology - School of Medicine - Shahid Beheshti University of Medical Sciences , Arabi ، Ali Reza Centre for processing and charactrization of nanostructred materials, School of mechanical engineering - University of Tehran , Soofi ، Dadkhoda Department of Medicine - Zabol University of Medical Sciences , Rajaei Ramsheh ، Saied Clinical Research Development Unit - Hajar Hospital - Shahrekord University of Medical Sciences , Ahmed ، Wasan Saad Department of Computer Science - Al-Turath University College , Moaref Pour ، Raziyeh Department of Oral and Maxillofacial surgery - School of Dentistry - Ahvaz Jundishapur University of Medical Sciences
Abstract :
In this research attempted to prepare hematite (α-Fe2O3) and silver doped hematite nanoparticles (Ag-doped α-Fe2O3 NPs) by using the aqueous extract of Prosopis farcta fruit. The synthesized NPs were identified through the results of X-ray Diffraction (XRD), Field Energy Scanning Electron Microscopy (FESEM), Raman, Energy Dispersive X-ray (EDX), and Vibrating Sample Magnetometer (VSM) technics. Accordingly, the NPs contained a spherical shape with a size range of 40-50 nm. Also, we surveyed their cytotoxic against human breast cancer (MCF-7) cell line, which showed a potential functionality at the concentration of 80 μg/mL. Therefore, the synthesized NPs can be proposed as an applicable candidate for medical applications.
Keywords :
Iron oxide nanoparticles , Silver nanoparticles , Breast cancer , Ag , doped α , Fe2O3 nanoparticles
Journal title :
Nanomedicine Research Journal
Journal title :
Nanomedicine Research Journal
