• Title of article

    Diastereoselective Aldol Reaction of (alpha)-Bromo Ketones with Aliphatic Aldehydes by Using Titanium(II) Chloride and Copper

  • Author/Authors

    Mukaiyama، Teruaki نويسنده , , Shiina، Isamu نويسنده , , Kagayama، Akifumi نويسنده , , Igarashi، Koji نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    -1156
  • From page
    1157
  • To page
    0
  • Abstract
    Highly diastereoselective aldol reaction of (alpha)-bromo ketones with aliphatic aldehydes was successfully carried out by using titanium(II) chloride and copper in dichloromethane at low temperature. Similarly, Reformatsky-type reaction of (alpha)-bromo thioester with aliphatic aldehydes was promoted under mild conditions to afford (beta)-hydroxy thioesters in good to moderate yields.
  • Keywords
    Model diagnosis , Restricted latent class models , Goodness of fit , Parametric bootstrap , Identifiability
  • Journal title
    CHEMISTRY LETTERS
  • Serial Year
    1999
  • Journal title
    CHEMISTRY LETTERS
  • Record number

    27920