Electrochemistry of Hypericin Incorporated into a Cationic Lipid Film on a Graphite Electrode in an Aqueous Medium

Quasi-reversible two-consecutive one-electron reduction processes of hypericin (Hyp) in an aqueous medium were achieved by incorporating Hyp into a cast film of a synthetic cationic lipid, dioctadecyldimethylammonium bromide (2C18N+Br-), coated on a basal-plane pyrolytic graphite (BPG) electrode. Importance of the electrostatic interaction between Hyp anions and the cationic sites in the matrix was suggested.