Title of article :
A Macrocyclic Sialic Acid Cluster as a Host, as an Adsorbate, and as a Ligand for Lectin and Virus
Author/Authors :
Aoyama، Yasuhiro نويسنده , , Fujimoto، Kazuhisa نويسنده , , Hayashida، Osamu نويسنده , , Guo، Chao-Tan نويسنده , , Hidari، Kazuya I.-P. Jwa نويسنده , , Suzuki، Yasuo نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
A calix[4]resorcarene-based macrocyclic octa(sialic acid) derivative 1d was prepared. It forms complexes with such guests as rose bengal in water. It forms a closely packed monolayer on an SPR sensor chip; a sialo-targeting lectin is readily adsorbed on the saccharide residues exposed to bulk water. Compound 1d also inhibits the hemagglutination of human erythrocytes and also cytopathic effect of MDCK (Madine-Darby canine kidney) cells mediated by human influenza A viruses at concentrations of 550 (mu)M.
Keywords :
Goodness of fit , Model diagnosis , Parametric bootstrap , Restricted latent class models , Identifiability
Journal title :
CHEMISTRY LETTERS
Journal title :
CHEMISTRY LETTERS
