• Title of article

    Lack of responsiveness to TGF-(beta)l in a thyroid carcinoma cell line with functional type I and type II TGF-(beta) receptors and Smad proteins, suggests a novel mechanism for TGF-(beta) insensitivity in carcinoma cells

  • Author/Authors

    Heldin، Nils-Erik نويسنده , , Bergstrom، Daniel نويسنده , , Hermansson، Annika نويسنده , , Bergenstrahle، Annika نويسنده , , Nakao، Atsuhito نويسنده , , Westermark، Bengt نويسنده , , Dijke، Peter ten نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    -78
  • From page
    79
  • To page
    0
  • Abstract
    Semianalytical transient equations for shallow subsurface transverse drainage systems installed in sloping lands are developed. They provide a general relationship between drain flow rates, water table elevations, and recharge rates. This relationship demonstrates that, depending on the recharge intensity, several drain flow rates can be observed at a given water table elevation. The recharge contribution is shown to depend on a water table shape factor and to decrease when the water table is low or the slope is steep. For very steep slopes, the rccharge intensity no longer influences the drain flow rate. These equations can be used to confirm previous results obtained in steady-state conditions and to determine precisely under which conditions slope needs to be considered in drainage design. They have been incorporated into the field drainage model SIDRA, which simulates hourly values of water table elevations and drain flow rates. The model predictions are compared with the predictions of a steady-state equation and a numerical model, which solves the Boussinesq equation (SLOP model).
  • Keywords
    SMADs , TGF-(beta)-signalling , Anaplastic , TGF-(beta) receptors , Thyroid carcinoma
  • Journal title
    MOLECULAR & CELLULAR ENDOCRINOLOGY
  • Serial Year
    1999
  • Journal title
    MOLECULAR & CELLULAR ENDOCRINOLOGY
  • Record number

    32270