CIRCADIAN PACEMAKER FUNCTION AND ENTRAINMENT DURING MATURATION OF TRANSGENIC HYPERTENSIVE TGR(mREN2)27 AND SPRAGUE-DAWLEY RATS

What are phase-response curves (PRCs)? How can they be measured? How should they be plotted? These questions and many other fascinating facets of PRCs are addressed in this review, including research topics in which phase-resetting data have provided crucial insights: entrainment, phototransduction, pacemaker mechanism, phase markers of the pacemaker, and gauges of oscillator amplitude. PRCs have enlightened us and will continue to be a valuable tool in clock research.