Author/Authors :
Richard B. Fair، نويسنده , , Duke University
Andrey Khlystov، نويسنده , , Duke University
Tina D. Tailor، نويسنده , , Duke University
Vladislav Ivanov، نويسنده , , Duke University
Randall D. Evans، نويسنده , , Duke University
Vijay Srinivasan، نويسنده , , Advanced Liquid Logic
Vamsee K. Pamula، نويسنده , , Advanced Liquid Logic
Michael G. Pollack، نويسنده , , Advanced Liquid Logic
Peter B. Griffin، نويسنده , , Stanford University
Jack Zhou، نويسنده , , Drexel University
، نويسنده ,
Abstract :
Digital-microfluidic lab-on-a chip (LoC) technology offers a platform for developing diagnostic applications with the advantages of portability, sample and reagent volume reduction, faster analysis, increased automation, low power consumption, compatibility with mass manufacturing, and high throughput. In addition to diagnostics, digital microfluidics is finding use in airborne chemical detection, DNA sequencing by synthesis, and tissue engineering. In this article, we review efforts to develop various LoC applications using electrowetting-based digital microfluidics. We describe these applications, their implementation, and associated design issues.