Microwave assisted synthesis of 2,3-disubstituted-4-thiazolidinones and their pharmacological screening

Six title compounds have been synthesized by condensation of substituted (4-mcthyl-2-quinolinyl)oxyacetic acid hydrazide (1) with aryl aldehydes followed by reaction with thioglycolic acid in dioxane under microwave irradiation. All the compounds are screened for their central nervous system and cardiovascular system activities.