Personality correlates of HIV vaccine trial participation

Individual differences in motivations and behaviors among HIV-negative participants in HIV vaccine trials remain unclear. 127 active participants in vaccine trials completed an anonymous questionnaire assessing motivations for trial participation, personality (as measured by the NEO-FFI), and perceived risk of HIV infection. Results revealed that Neuroticism was positively related to perceived risk of HIV infection, a desire for HIV testing, and a desire for protection from HIV as motivation for trial participation. Implications for personality research in HIV vaccine trials are discussed.