Title of article
Pustular allergic contact dermatitis to isoconazole nitrate
Author/Authors
Aneta Lazarov، نويسنده , , Arieh Ingber، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
2
From page
229
To page
230
Abstract
The topical imidazole antimycotics are widely used and are an infrequent cause of contact allergy. We report on a woman, who developed an unusual clinical picture of allergic contact dermatitis, namely papulopustular reaction, evoked by an isoconazole nitrate-containing cream. The histopathologic changes included subcorneal pustules, spongiosis, and an inflammatory infiltrate composed mainly of lymphocytes and some eosinophils and neutrophils. The patient demonstrated a severe vesicular reaction to isoconzole nitrate as is and at an imidazoles concentration of 0.5%. No cross-reactivity with other imidazole antimycotics was noted.
Journal title
Dermatitis
Serial Year
1997
Journal title
Dermatitis
Record number
461034
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