Title of article :
Prostaglandins for induction of second-trimester termination and intrauterine death
Author/Authors :
Suk Wai Ngai، نويسنده , , Oi Shan Tang، نويسنده , , Pak Chung Ho، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
The introduction of synthetic prostaglandin has revolutionized the treatment protocol for induction of second-trimester abortion and intrauterine death. Gemeprost is the only licensed synthetic prostaglandin analogue for second-trimester abortion in the United Kingdom. However, it is expensive and needs to be stored in a refrigerator. Misoprostol is marketed for use in the prevention and treatment of peptic ulcer. It is inexpensive and can be stored at room temperature. It has been widely used for induction of second-trimester abortion and intrauterine death. Misoprostol, 400 μg given vaginally every 3 hours, is probably the optimal regimen for second-trimester abortion. The combination of misoprostol and mifepristone significantly reduced the induction-to-abortion interval when compared with the misoprostol-only regimen. In addition, misoprostol can also be used as a cervical priming agent prior to dilatation and evacuation in second-trimester abortion
Keywords :
prostaglandin , Author Keywords: second-trimester abortion , intrauterine death
Journal title :
Best Paractice and Research Clinical Obstetrics and Gynaecology
Journal title :
Best Paractice and Research Clinical Obstetrics and Gynaecology