• Title of article

    Disseminated intravascular coagulation and purpura fulminans secondary to infection

  • Author/Authors

    Saul N. Faust، نويسنده , , Robert S. Heyderman، نويسنده , , Stephen Michael Levin، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    19
  • From page
    179
  • To page
    197
  • Abstract
    Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.
  • Keywords
    pathophysiology , Gram-negative , clinical trials , Therapy , disseminated intravascular coagulation (DIC) , purpura fulminans , meningococcal , tissue factor (TF) , tissue factor pathwayinhibitor (TFPI) , antithrombin (ATIII) , thrombomodulin (TM) , protein C (PC)/activated proteinC (APC) , tissue plasminogen activator (tPA).
  • Journal title
    Best Practice and Research Clinical Haematology
  • Serial Year
    2000
  • Journal title
    Best Practice and Research Clinical Haematology
  • Record number

    467379