Delivery delivery of medication by iontophoresis to treat post-burn hypertrophic scars: investigation of a new electronic technique

At present, direct current (DC) and pulsed direct current (PDC) methods are used for iontophoresis. Although the DC field has high efficiency, it exhibits some side-effects. The PDC field has little side-effects, but the efficiency is lower. In this study, a new iontophoretic drug device was designed for providing the maximal efficiency with the minimal side-effects. Tests of animal and human models showed that the permeation rate of the new field was higher than that of PDC and DC fields, and side-effects were lower than that of the DC field.