Title of article :
Insulin autoimmunity: prediction/precipitation/prevention type 1A diabetes
Author/Authors :
George S. Eisenbarth، نويسنده , , Hiroaki Moriyama، نويسنده , , David T. Robles، نويسنده , , Edwin Liu، نويسنده , , Liping Yu، نويسنده , , Sunanda Babu، نويسنده , , Maria Redondo، نويسنده , , Peter Gottlieb، نويسنده , , Dale Wegmann، نويسنده , , Marian Rewers، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
7
From page :
139
To page :
145
Abstract :
Type 1 diabetes of both the NOD mouse and man is associated with autoimmunity directed against insulin which is the only beta cell specific autoantigen identified to date. One can use autoantibodies to insulin to predict diabetes, use insulin peptides to create insulin autoantibodies, insulitis and diabetes, and use insulin or its peptides in animal models to prevent diabetes. An expanding set of resources are now available for the development and testing in man of therapies to prevent type 1 diabetes, and a number of trials utilizing insulin peptides are now underway.
Keywords :
autoantibody , autoimmune , Type 1 diabetes , Variable nucleotide tandem repeat
Journal title :
Autoimmunity Reviews
Serial Year :
2002
Journal title :
Autoimmunity Reviews
Record number :
474330
Link To Document :
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