Title of article
CD20: A target antigen for immunotherapy of autoimmune diseases
Author/Authors
Federico Perosa، نويسنده , , Elvira Favoino، نويسنده , , Maria Antonietta Caragnano، نويسنده , , Marcella Prete، نويسنده , , Franco Dammacco، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
6
From page
526
To page
531
Abstract
This article reviews the role of CD20 antigen in B cell function and the effectiveness and limits of passive immunotherapy with anti-CD20 monoclonal antibody (Rituximab) in the treatment of autoimmune (or immune-mediated) diseases. Active immunotherapy is a more feasible way to control these chronic diseases. A peptide that mimics the CD20 epitope recognized by Rituximab is employed to stimulate the host immune response against CD20.
Keywords
immunotherapy , vaccine , peptide , rituximab , Autoimmunity , CD20 , Mimotope
Journal title
Autoimmunity Reviews
Serial Year
2005
Journal title
Autoimmunity Reviews
Record number
474611
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