Title of article
Surface-based DNA computing operations: DESTROY and READOUT
Author/Authors
Wang، Liman نويسنده , , Liu، Qinghua نويسنده , , Frutos، Anthony G. نويسنده , , Gillmor، Susan D. نويسنده , , Thiel، Andrew J. نويسنده , , Strother، Todd C. نويسنده , , Condon، Anne E. نويسنده , , Corn، Robert M. نويسنده , , Lagally، Max G. نويسنده , , Smith، Lloyd M. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
-188
From page
189
To page
0
Abstract
DNA computing on surfaces is where complex combinatorial mixtures of DNA molecules are immobilized on a substrate and subsets are tagged and enzymatically modified (DESTROY) in repeated cycles of the DNA computation. A restriction enzyme has been chosen for the surface DESTROY operation. For the READOUT operation, both cycle sequencing and PCR amplification followed by addressed array hybridization were studied to determine the DNA sequences after the computations.
Keywords
Enzyme systems , Transient phase , steady state , Rapid equilibrium , Kinetic equations , Computer program
Journal title
BioSystems
Serial Year
1999
Journal title
BioSystems
Record number
47482
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