Title of article
Interstitial cells of Cajal and purinergic signalling
Author/Authors
G. Burnstock، نويسنده , , S. Lavin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
68
To page
72
Abstract
Interstitial cells of Cajal (ICC) in the guinea pig intestine, identified by the tyrosine kinase receptor, c-Kit, have been shown with immunohistochemistry to express nucleotide P2X2 and P2X5 receptors. P2X5 receptors have also been demonstrated on interstitial cells in the mouse ileum. It is speculated that release of ATP from enteric nerves, enteric glial cells or from contracting smooth muscle may provide a feedback mechanism for pacemaker activity in the intestine.
Keywords
ATP , Smooth muscle contraction , enteric nerves , Purinergic , Interstital cells of Cajal , P2X purinoceptors , Pacemaker activity , Guinea pig intestine , Mouse intestine
Journal title
Autonomic Neuroscience: Basic and Clinical
Serial Year
2002
Journal title
Autonomic Neuroscience: Basic and Clinical
Record number
475516
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