Abstract :
We simulated the diffusion of glutamate, following the release of a single vesicle from a presynaptic terminal, in the synaptic cleft by using a Brownian diffusion model based on Langevin equations. The synaptic concentration time course and the time course of quantal excitatory post-synaptic current have been analyzed. The results showed that they depend on the number of receptors located at post-synaptic membrane. Their time course are dependent both on the total number of the post-synaptic receptors and on the eccentricity of the presynaptic glutamate vesicle.
Keywords :
Neural operations , Logic gates , Set operational gates , Neurons as measuring devices , Subadditivity , Supra-additivity , Single spikes -burst transformations , Spikes , Pulse code , Burst operations , Arithmetic gates
