Author/Authors :
F Carlucci، نويسنده , , A Tabucchi، نويسنده , , D Perrett، نويسنده , , Pizzichini، G. نويسنده , , F Rosi، نويسنده , , R Pagani، نويسنده , , E Marinello، نويسنده ,
Abstract :
Purine nucleotide metabolism has been studied in T-lymphocyte population in healthy subjects and in AIDS bearing patients. Nucleotide content was determined by HPLC. The overall rate of purine nucleotide synthesis was measured following the incorporation of 14C-formate into the nucleotides of a T cell suspension. The authors discuss the results, which indicate interesting variations in nucleotide content and a lower nucleotide synthesis, determined by kinetic studies.
