Author/Authors :
Pascale Nguyen Van Binh، نويسنده , , Dong Zhou، نويسنده , , Françoise Baudouin، نويسنده , , Chantal Martin، نويسنده , , Martine Radionoff، نويسنده , , Helene Dutertre، نويسنده , , Veronique Marchand، نويسنده , , Marc Thevenin، نويسنده , , Jean-Michel Warnet، نويسنده , , Huynh Thien Duc، نويسنده ,
Abstract :
Cigarette smoke condensate administered to C57BL/6 mice led to a decrease in the primary antibody response to OVA (hen egg albumin) antigen. Selenium (Se)-supplementation allowed to relieve significantly this inhibition. Moreover, even being not supplemented with Se, a preparation was found devoid of inhibitory effects. Furthermore, the presence of Se-supplemented tobacco smoke condensate at the time of antigen priming, contributed to an enhanced secondary antibody response.
