Synthesis of lipids on the micelle/water interface using inorganic phosphate and an alkene oxide

Liposomes can be considered as a model for a protocell in the context of the origin of life. These self-organising systems can self-reproduce under certain experimental conditions. Herein we demonstrate the ability of another lipid aggregate, micelles, to catalyse a reaction leading finally to the formation of new lipids. In contrast to other published work, where the lipids are products of a hydrolysis reaction, here the lipids are built up from simple precursors. In addition, we observe a transformation of micelles into liposomes.