Abstract :
This article introduces The Family Health Project, a multidisciplinary longitudinal investigation of children and their HIV-infected mothers and a comparison sample from the same inner-city environment. The background literature, purpose of the Project, advantages and challenges of interdisciplinary collaboration, methods of study including participant and design issues, overview of preliminary findings, clinical implications, and social policy implications are presented. Beyond introducing a new and important project examining a neglected sample in our society, the present article is intended to provide useful guidelines for other multidisciplinary large-scale clinical research projects.