Application of the EMIT 2000 Tacrolimus assay on the Abbott Architect c8000 high volume clinical chemistry analyzer

Objectives: Evaluation of the performance of the EMIT 2000 Tacrolimus assay on the Abbott Architect c8000 analyzer. Design and Methods: Imprecision studies were performed and patient samples were assayed by EMIT assay and by LC-MS/MS. Results: Limit of quantification was established at 2.8 μg/L. A positive bias of 17.5% between results measured on EMIT and on LC-MS/MS was detected. Conclusions: EMIT 2000 Tacrolimus assay is suitable for automated analyses of Tacrolimus on the Architect c8000.