Author/Authors :
Emmanuel Bissé، نويسنده , , Thomas Epting، نويسنده , , Gabriele K?gel، نويسنده , , Rima Obeid، نويسنده , , Klaus Gempel، نويسنده , , Daniela Huzly، نويسنده , , Klaus Fuhrmann، نويسنده , , Boris Rolinski، نويسنده , , Wolfgang Herrmann، نويسنده , , Heinrich Wieland، نويسنده ,
Abstract :
Objective:
To evaluate the clinical use of Homocysteine–Primavette®, a new blood collection medium for total homocysteine (tHcy) assay.
Methods:
The agreement between baseline tHcy and tHcy in stabilized samples (40 h) was assessed for FPIA, HPLC, GC-MS, LC-MS, and ICL.
Results:
tHcy concentrations in whole blood were stable for 40 h in Hcy–Primavette tubes.
Conclusion:
Primavette tubes are a good alternative for the accurate tHcy measurement and no readjustment of reference intervals is needed.
Keywords :
Total homocysteine (tHcy) , tHcy stabilizers , Preanalytical conditions , Sodium fluoride effect on tHcy
