• Title of article

    Polypyrrole-polyvinyl sulphonate film based disposable nucleic acid biosensor

  • Author/Authors

    Singh، Surinder P. نويسنده , , Prabhakar، Nirmal نويسنده , , Arora، Kavita نويسنده , , Pandey، Manoj K. نويسنده , , Singh، Harpal نويسنده , , Malhotra، Bansi D. نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2007
  • Pages
    -5
  • From page
    6
  • To page
    0
  • Abstract
    Double stranded calf thymus deoxyribonucleic acid entrapped polypyrrole-polyvinyl sulphonate (dsCT-DNA-PPy-PVS) films fabricated onto indium-tin-oxide (ITO) coated glass plates have been used to detect organophosphates such as chlorpyrifos and malathion. These disposable dsCT-DNA-PPy-PVS/ITO bioelectrodes have been characterized using cyclic voltammetry, Fourier-transform-infra-red (FTIR) spectroscopy and atomic force microscopy (AFM), respectively. These biosensing electrodes have a response time of 30 s, are stable for about 5 months when stored in desiccated conditions at 25 °C and can be used to amperometrically detect chlorpyrifos (0.00160.025 ppm) and malathion (0.17-5.0), respectively. The additive effect of these pesticides on the amperometric response of the disposable dsCT-DNA-PPy-PVS/ITO bioelectrodes has also been investigated.
  • Keywords
    Nucleic acid biosensor , Polypyrrole-polyvinyl sulphonate , Deoxyribose nucleic acid , Electrochemical entrapment , Malathion , Chlorpyrifos
  • Journal title
    Analytica Chimica Acta
  • Serial Year
    2007
  • Journal title
    Analytica Chimica Acta
  • Record number

    49225