Title of article :
We have found and reported on all injuries to the head and neck described in Homerʹs Iliad, and give several particularly graphic examples.
Author/Authors :
Masaru Sugiyama ، نويسنده , , Ujjal Kumar Bhawal، نويسنده , , Makoto Kawamura، نويسنده , , Yasuki Ishioka، نويسنده , , Hideo Shigeishi، نويسنده , , Koichiro Higashikawa، نويسنده , , Nobuyuki Kamata، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
We examined 66 oral squamous cell carcinomas (OSCCs) for human papillomavirus-16 (HPV-16) infection to evaluate its prognostic significance. Cox regression analysis of 5-year survival demonstrated that patients without nodal metastasis or with intratumoural HPV-16 showed better prognoses compared with each counterpart. In Kaplan-Meier survival analysis, nodal status but not HPV-16 status was statistically significant. The 5-year survival rate of HPV-16 positive patients without nodal metastasis (94%) was extremely high, compared with that of HPV-16 negative patients with nodal metastasis (25%). These results suggest that HPV-16 status as well as nodal status may provide prognostic significance in patients with OSCC.
Keywords :
Human papillomavirus-16 , Clinical Correlates , multivariate analysis , 5-year survival , Oral squamous cell carcinoma
Journal title :
British Journal of Oral and Maxillofacial surgery
Journal title :
British Journal of Oral and Maxillofacial surgery