Author/Authors :
Grant M. Reeves، نويسنده , , Barbara R. Mccreadie، نويسنده , , Shu Chen، نويسنده , , Andrzej T. Galecki، نويسنده , , David T. Burke، نويسنده , , Richard A. Miller، نويسنده , , Steven A. Goldstein، نويسنده ,
Abstract :
The aim of this study was to examine effects of polymorphic genes on vertebral bone morphology and mechanical properties. Genotypes from 525 18-month-old female mice were compared to geometric traits obtained from micro-computed tomography and mechanical properties from compression testing. Genetic markers were associated with traits on at least 13 different chromosomes, demonstrating the complexity of genetic control over vertebral form, function and aging.
Keywords :
Genetic , Mice , Mechanical property , Geometry , quantitative trait loci
