Title of article
Characterization of Direct Readout Contacts of the Myb DNA-Binding Domain,
Author/Authors
A. SCHURMANN، نويسنده , , R. Sokolowski، نويسنده , , M. Haas، نويسنده , , H. Wolfes، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
6
From page
464
To page
469
Abstract
The Myb protein contacts its recognition sequence by means of direct protein–DNA interactions. We used site-directed mutagenesis in order to substitute amino acids crucial for these contacts and probed the mutant proteins for their DNA-binding and transactiving activities. We could show that amino acids involved in direct readout contacts do not contribute equivalently in the recognition process
Keywords
c-Myb , DNA–protein interactions , DNA-binding domain
Journal title
Blood Cells, Molecules and Diseases
Serial Year
2001
Journal title
Blood Cells, Molecules and Diseases
Record number
498416
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