Does nutritional risk, as assessed by Nutritional Risk Index, increase during hospital stay? A multinational population-based study

Background: Progressive nutritional depletion has been reported during hospital stay. This prospective study compared the proportion of nutritional risk at hospital admission in three European countries and further evaluated nutritional risk at late versus early phase of hospitalization in one hospital. Methods: Nutritional risk was determined in Geneva, Switzerland (n ¼ 652), Berlin, Germany (n ¼ 621) and Nice, France (n ¼ 107) at hospital admission, and during hospital stay (0–100 d) in Nice (n ¼ 527) by the Nutritional Risk Index (NRI) ¼ (1.519 serum albumin, g/l)+41.7 (present weight/usual weight). NRI score of 4100: no risk (NR); 97.5–100: mild risk; 83.5–97.5: moderate risk (MR); p83.5: severe risk (SR). Logistic regressions were used to determine the odds ratios (OR) between MR or SR and length of hospital stay (LOS)X16 d compared to 1–15 d or nutritional assessment at 16–100 d compared to 1–15 d of hospitalization. Results: Patients, assessed at hospital admission, who were hospitalized 416 d were more likely (Po0.001) to be at MR (OR 2.0, CI 1.4–3.0) or SR (OR 3.3, CI 1.7–6.2) than patients hospitalized 1–15 d. Nice patients assessed at 16–100 d were more likely (Po0.001) to be at MR (OR 5.4, CI 2.1–14.3) and SR (OR 14.7, CI 5.4–40.0) than patients assessed at 1–15 d of hospitalization. Conclusions: The risk of MR or SR by NRI was greater in patients assessed during hospitalization than in patients assessed at hospital admission, which suggests that patients evaluated later during hospitalization are at greater risk than patients evaluated in the early phase of hospitalization. Ongoing assessment during