Title of article :
An audit of outcomes in colorectal cancer in China
Author/Authors :
X.Y. Zong، نويسنده , , Y.Q. Shi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
5
From page :
169
To page :
173
Abstract :
Aim This study was designed to analyses the correlation between the extent of lymph node excision and the prognosis of colorectal cancer and to discuss the clinical significance of excision of lymph nodes adjacent to mesenteric artery pedicle. Methods A total of 1409 patients with colorectal cancer who had the primary radical operation in our hospital during 1985 to 2000 was analyzed in this study. They were divided into two groups according to whether undergone an excision of lymph nodes adjacent to mesenteric artery pedicle. There were 857 patients in the excision group and 552 patients in the non-excision group. Comparison of prognoses was based on the follow-up results. Results The 1-year, 3-year and 5-year overall survival rates of the excision group were 90%, 81% and 77%, while those of the non-excision group were 91%, 84% and 79%, respectively. The 1-year, 3-year and 5-year tumor-free survival rates of excision group were 90%, 79% and 75%, while those of the non-excision group were 90%, 83% and 76%. Kaplan–Meier analysis did not show any difference in overall survival rate or tumor-free survival rate between these two groups (P > 0.05). After follow-up of 12 to 289 months there were 42 cases of local recurrence and 79 cases of metastases in the excision group. In the non-excision group local recurrence occurred in 30 cases and 60 patients had metastases. There was no difference in the rates of local recurrence and metastasis between these two groups. Multivariate correlation analyses showed that the excision of lymph nodes adjacent to mesenteric artery pedicle was not statistically correlated to recurrence, metastasis and survival time after radical operation of colorectal cancer. Conclusion In radical operation of colorectal cancer it is not necessary to perform excision of lymph nodes adjacent to mesenteric artery pedicle which is not correlated to prognosis.
Keywords :
prognosis , Radical operation , Colorectal Cancer , lymph node excision
Journal title :
European Journal of Surgical Oncology
Serial Year :
2007
Journal title :
European Journal of Surgical Oncology
Record number :
511356
Link To Document :
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