Title of article
Role of dendritic and follicular dendritic cells in HIV infection and pathogenesis
Author/Authors
Geraldine Grouard، نويسنده , , Edward A Clark، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
5
From page
563
To page
567
Abstract
Dendritic cells (DCs) and follicular dendritic cells (FDCs) play important roles in HIV-mediated pathogenesis. Recent studies have defined new DC subsets and shown that DCs in lymphoid mucosa can both harbor virus and stimulate its spread into CD4+ T cells. FDCs harbor unspliced HIV mRNA and immune complexed virus, but not actively infectious virus, yet these cells are a key regulated reservoir of virions.
Journal title
Current Opinion in Immunology
Serial Year
1997
Journal title
Current Opinion in Immunology
Record number
511651
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