Author/Authors :
P. A. Culbert، نويسنده , , M. J. Adam، نويسنده , , E. T. Hurtado، نويسنده , , J. M. A. Huser، نويسنده , , S. Jivan، نويسنده , , J. Lu، نويسنده , , T. J. Ruth، نويسنده , , S. K. Zeisler، نويسنده ,
Abstract :
The synthesis of [18F]FDG using tetrabutylammonium bicarbonate has been successfully modified to accommodate automation using the Optomux® control system. Noteworthy changes to the methods previously reported are the addition of a small ion exchange column which serves to quantitatively trap [18F]fluoride from the target water and the extensive use of thermocouple and radiation detector feedback for process control. The radiochemical yields observed over 30 runs are: 50.3 ± 9% decay corrected and 34.6 ± 6% decay uncorrected.