Title of article
A complete remote-control system for reliable preparation of [18F]altanserin
Author/Authors
Ping-Zhong Tan، نويسنده , , Ronald M. Baldwin، نويسنده , , Robert Soufer MD FACC، نويسنده , , Pradeep K. Garg، نويسنده , , Dennis S. Charney، نويسنده , , Robert B. Innis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
5
From page
923
To page
927
Abstract
A complete remote control system was constructed for production of the PET 5-HT2A ligand [18F]altanserin by nitro-for-fluoro exchange. Comparing with published methods, the key features include (1) conducting azeotropic distillation and nucleophilic displacement in an open vessel heated by a commercial microwave oven; (2) purifying the product by a single HPLC procedure and (3) removing HPLC solvent by solid phase extraction. The preparation took 114 min with 23% yield and high quality.
Journal title
Applied Radiation and Isotopes
Serial Year
1999
Journal title
Applied Radiation and Isotopes
Record number
540387
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