Title of article
First BNCT treatment of a skin melanoma in Argentina: dosimetric analysis and clinical outcome
Author/Authors
S. J. Gonz?lez، نويسنده , , M. R. Bonomi، نويسنده , , G. A. Santa Cruz، نويسنده , , H. R. Blaumann، نويسنده , , O. A. Calzetta Larrieu، نويسنده , , P. Menéndez، نويسنده , , R. Jimenez Rebagliati، نويسنده , , J. Longhino، نويسنده , , D. B. Feld، نويسنده , , M. A. Dagrosa، نويسنده , , C. Argerich، نويسنده , , S. G. Castiglia، نويسنده , , D. A. Batistoni، نويسنده , , S. J. Liberman، نويسنده , , B. M. C. Roth، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
1101
To page
1105
Abstract
A Phase I/II protocol for treating cutaneuos melanomas with BNCT was designed in Argentina by the Comisión Nacional de Energía Atómica and the medical center Instituto Roffo. The first of a cohort of thirty planned patients was treated on October 9, 2003. This article depicts the protocol-based procedure and describes the first clinical case, treatment regime and planning, patient irradiation, retrospective dosimetric analysis and clinical outcome. Considering the low acute skin toxicity and the complete response in 21 of the 25 subcutaneous melanoma nodules treated, a second irradiation was performed in a different location of the extremity of the same patient. The corresponding clinical outcome is still under evaluation.
Keywords
treatment planning , clinical trial , Skin melanomas , BNCT
Journal title
Applied Radiation and Isotopes
Serial Year
2004
Journal title
Applied Radiation and Isotopes
Record number
541880
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