Solubility of compositions in the system CaTixZr4 − x(PO4)6 with X = 0–4

In vitro solubility tests of granulated materials and coatings were carried out on some compositions in the system CaTixZr4 − x(PO4)6 with x = 0–4, in order to find a biocompatible material which is less soluble than hydroxyapatite (HA) and can also be used as bone substitution material. The granulated materials were leached out by using circulating equipment in which the solvent flows in circulation. The coatings were tested under conditions where the sample containers undergo a circular movement. The results show better chemical stability of nearly all tested compounds compared with HA for both granulated materials and coatings.