Title of article
The gastrointestinal transit profile of 14C-labelled poly(acrylic acids): : an in vivo study
Author/Authors
Robert G. Riley، نويسنده , , Keith L. Green، نويسنده , , John D. Smart، نويسنده , , John Tsibouklis، نويسنده , , J. Alf Davis، نويسنده , , Frank Hampson، نويسنده , , Peter W. Dettmar، نويسنده , , William R. Wilber، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
7
From page
1861
To page
1867
Abstract
The gastrointestinal distribution profiles for three 14C-labelled poly(acrylic acid)s of different average molecular weights and degrees of cross-linking have been established using the rat model. Despite initial differences in transit times and retention characteristics, these structural features were found to be of little influence to the overall gastrointestinal transit of the materials under consideration. No evidence for the systemic absorption of any of the polymers could be identified.
Keywords
C-poly(acrylic acid) , In Vivo , Polymer retention , mucoadhesion
Journal title
Biomaterials
Serial Year
2001
Journal title
Biomaterials
Record number
543898
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