Title of article
Role of acid attack in the in vitro bioactivity of a glass-ceramic of the 3CaO•P2O5-CaO•SiO2-CaO•MgO•2SiO2 system
Author/Authors
J. Roman، نويسنده , , A. J. Salinas، نويسنده , , M. Vallet-Regi، نويسنده , , J. M. Oliveira، نويسنده , , R. N. Correia، نويسنده , , M. H. Fernandes، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
7
From page
2013
To page
2019
Abstract
A non-bioactive glass-ceramic (GC13) that contains hydroxyapatite (Ca5(PO4)3OH), diopside (CaMg(SiO3)2) and althausite (Mg2PO4OH) as crystalline phases has been obtained by thermal treatment of a parent bioactive glass (G13) of nominal composition (wt%) 40.0 CaO–34.5 SiO2–16.5 P2O5–8.5 MgO–0.5 CaF2. To induce bioactivity, GC13 was chemically treated with 1 HCl for different periods of time. After chemical etching the in vitro studies showed formation of an apatite-like surface layer. In this article the influence of etching time both on the surface composition of the glass-ceramic and on the growth rate of the apatite layer is studied. It is concluded that the presence of hydroxyapatite in the glass-ceramic, associated to microstructural fluctuations, can favour apatite deposition in vitro.
Keywords
Bioceramics , In vitro studies , Bioactive glass-ceramics , Bioactivity induction , Surface morphology
Journal title
Biomaterials
Serial Year
2001
Journal title
Biomaterials
Record number
543915
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