Title of article :
In vivo conjunctival reconstruction using modified PLGA grafts for decreased scar formation and contraction
Author/Authors :
Sang-Young Lee، نويسنده , , Jung Hwan Oh، نويسنده , , Jae Chan Kim، نويسنده , , Young Ha Kim، نويسنده , , Soo Hyun Kim، نويسنده , , Jung Woo Choi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Pages :
11
From page :
5049
To page :
5059
Abstract :
The in vivo reconstruction of conjunctiva was investigated by using modified poly(lactide-co-glycolide) (PLGA) 50/50 scaffolds. The porous PLGA matrices were prepared by a solvent-casting particulate-leaching method with NaCl, then modified with collagen, hyaluronic acid (HA) or/and human amniotic membrane (AM) component. The growth of corneal epithelial cells and human stromal fibroblasts on the scaffolds was investigated in vitro. All the modified PLGA scaffolds demonstrated enhanced cell adhesion and proliferation as compared to PLGA untreated, and the number of cells proliferated after 1 week was increased in the order of PLGA
Keywords :
Modified PLGAgraft , Low contraction and scar , Conjunctival reconstruction , Rabbit model
Journal title :
Biomaterials
Serial Year :
2003
Journal title :
Biomaterials
Record number :
545148
Link To Document :
