Author/Authors :
Tadashi Kokubo، نويسنده , , Masayuki Hanakawa، نويسنده , , Masakazu Kawashita، نويسنده , , Masahiko Minoda، نويسنده , , Toshiyuki Beppu، نويسنده , , Takeaki Miyamoto، نويسنده , , Takashi Nakamura، نويسنده ,
Abstract :
Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)2 aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite–chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material.
Keywords :
apatite , Carboxymethylated chitin , Non-woven fabric , Carboxyl groups , Biomimetic process , Simulated body fluid
