Author/Authors :
Gemma Quincoces، نويسنده , , Iv?n Pe?uelas، نويسنده , , Marta Valero، نويسنده , , Patricia Serra، نويسنده , , Mar?a Collantes، نويسنده , , Josep Mart?-Climent، نويسنده , , Javier Arbizu، نويسنده , , Mar?a José Garc?a-Velloso، نويسنده , , José ?ngel Richter، نويسنده ,
Abstract :
We herein describe a simple setup for the automated simultaneous synthesis of l-[methyl-11C]methionine and N-[methyl-11C]choline by solid-supported methylation . The setup is extremely simple and easy to adapt to other automated systems and due to its versatility, the method can be utilized for the production of other radiopharmaceuticals requiring a simple [11C]methylation step. Furthermore, it can be used for multiple simultaneous synthesis.
