Author/Authors :
Bijayeswar Vaidya، نويسنده , , Helen Imrie، نويسنده , , Petros Perros، نويسنده , , Jane Dickinson، نويسنده , , Mark I. McCarthy، نويسنده , , Pat Kendall-Taylor، نويسنده , , Simon HS Pearce، نويسنده ,
Abstract :
Smoking and demographic variables are known to be risk factors for the development of thyroid-associated orbitopathy (TAO) among patients with Gravesʹ hyperthyroidism, but a firm genetic basis for TAO has not been established. We show that the presence and severity of TAO are associated with an allele of the cytotoxic T lymphocyte antigen-4-gene.
