Title of article
Evidence for presence of lgG4 anti-immunoglobulin autoantibodies in all human beings Original Research Article
Author/Authors
C Hennig، نويسنده , , L Rink، نويسنده , , H Kirchner، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
2
From page
1617
To page
1618
Abstract
lgG4 anti-IgG autoantibodies were found to be present in all serum samples from a group of healthy people; IgG4 anti-lgA and anti-lgE were present in only 13 of 218 (6%) and 8 of 218 (3·5%) samples, respectively. These antibodies also showed affinities towards animal immunoglobulins. We suggest that lgG4 anti-lgA antibodies (the strongest found heterophilic immunoglobulins) are responsible for most artifacts obtained with commercial ELISA systems.
Journal title
The Lancet
Serial Year
2000
Journal title
The Lancet
Record number
551794
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