Author/Authors :
Gunther Gastl، نويسنده , , Gilbert Spizzo، نويسنده , , Peter Obrist، نويسنده , , Martina Dünser، نويسنده , , Gregor Mikuz، نويسنده ,
Abstract :
The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immuno-histochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35·6% of samples and was associated with poor disease-free and overall survival.
