Author/Authors :
A. W. Artenstein، نويسنده , , A. E. Brown، نويسنده , , T. C. VanCott، نويسنده , , J. R. Mascola، نويسنده , , D. S. Burke، نويسنده , , J. Coppola، نويسنده , , E. Galbarini، نويسنده , , P. Schonbrood، نويسنده , , J. K. Carr، نويسنده , , E. Sanders-Buell، نويسنده , , F. E. McCutchan، نويسنده ,
Abstract :
There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.
